The sequel to Scythe sends players on a new adventure into Siberia, where a massive meteorite crashed near the Tunguska River, awakening ancient corruption. An expedition led by Dr. Tarkovsky ventures into the taiga to learn about the meteorite and its impact on the land. Itching for adventure, heroes from the war privately fund their own expeditions to Siberia, hoping to find artifacts, overcome challenges, and ultimately achieve glory.

Expeditions is a competitive, card-driven, engine-building game of exploration. It is designed to evoke similar feelings to Scythe even though the mechanisms are different: Play cards to gain power, guile, and unique worker abilities; move your mech to mysterious locations and gain cards found among the tiles; use workers, items, meteorites, and quests to enhance your mech; and use power and guile to vanquish corruption.

The Ironclad Edition of Expeditions features 5 large metal mechs (instead of plastic miniatures) and silicon base snaps (instead of plastic), as well as an individually numbered box with foil lettering.